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Fabulous Fungi: The Best Edible Mushrooms to Help with Everything from Treating Cancer to Lowering Risk of Depression

Mushrooms are great tasting--full of that unquantifiable ‘umami’ flavor, but did you know they are also one of nature’s most remarkable natural remedies for many mental and physical illnesses? 

Mushrooms have so many uses in our diet including flavoring drinks, adding a savory addition to pizzas, salads, baked yams, omelettes, holiday side dishes, and more. And they are definitely an important staple in a plant-based diet, particularly in those dishes where the ‘meaty’ quality is missed. 

In addition to the benefits of eating mushrooms, there are myriad other uses of this fabulous fungi that have been known to Chinese culture dating back centuries. 

These are some of the mushrooms in the dishes I love to make and the products I swear by. The benefits of these mushrooms run the whole gamut from  health, nutrition, immunity, brain function, and even beauty!


Incredibly rare in the wild, reishi mushrooms grow at the base of deciduous trees such as maple and are also known as the ‘mushroom of immortality.’ This might explain why they have had such a firm place in Chinese medicine for thousands of years. 

Reishi are known to have antioxidant properties, and have been of increasing interest in the treatment of cancer. This is due to beta-glucans and their ability to enhance tumor response to chemotherapy by sharpening the body’s own immune system. 

In addition, the plant sterols found in reishi mushrooms act as steroid precursors and can help in lowering cholesterol levels in those with mild elevation, according to one trial. 

Because of its slightly nutty, woody flavor, reishi is often added to teas and coffees. 


Found on the back of birch trees, the blackened charcoal appearance of chaga comes from the large amount of melanin, a type of pigmentation that we actually have in our skin. 

Most commonly seen in Russian forests as a parasitic tree infection, chaga has been historically made into a fine powder and brewed as a tea or coffee, which releases the beta-glucans renowned for their selectivity in killing cancer cells. 

It is also suggested that chaga mushrooms can reduce fatigue and increase cognitive performance, but they should be consumed only in small amounts as they are very high in oxalates, a contributor to kidney stones.

Lion’s Mane

The lion’s mane fungus has many different names, including the very apt ‘pom-pom mushroom’. Found across North America, Europe, and Northern Asia, it has been used as medicine for hundreds of years. 

Lion’s mane is known for its neuroprotective and nootropic effects which go much further than simply preserving brain cells. These effects can actually enhance memory and brain function. This is achieved by increasing nerve growth factor levels in the brain, growing brain cell insulation, or myelination, and improving long-term electrical signals. 

As if this was not enough, lion’s mane has anxiolytic effects and anti-inflammatory properties. Its only apparent downside is that it may cause hypersensitivity in those with allergies or asthma, much like non-steroidal anti-inflammatory drugs, and so it’s generally advised that those affected should avoid lion’s mane. 

In terms of cooking inspiration, lion’s mane is particularly delicious sautéed over medium heat with a sprinkle of Himalayan salt, black pepper, and chopped fresh thyme.


Maitake, ‘the dancing mushroom’ or ‘hen-of-the-wood’, grows in clusters at the bottom of large, well-established trees such as oaks. It is native to China, Northern Japan, and North America, and has been held in high esteem for thousands of years in Japanese and Chinese herbal medicine. 

A groundbreaking 2009 trial by Memorial Sloan-Kettering Cancer Center showed that the mushroom stimulated the immune system in patients receiving treatment for breast cancer by encouraging the activity of natural killer cells. 

In addition, maitake has been reported to have an anti-diabetic effect lowering blood sugar levels via a naturally occurring alpha-glucosidase inhibitor. 

In the kitchen, break maitake into small pieces by hand to preserve their natural texture, and add as a topping to homemade galettes or as a staple in a soba and soy broth.


One of the most famous of all the edible mushrooms, shiitake is native to Eastern Asia and actually makes up around 25% of the world’s yearly mushroom crop! 

Shiitake have less than one percent fat as a raw food, and are rich in those elusive B-vitamins. In terms of mushroom fiber, oyster and shiitake mushrooms have the most fiber at 2g per serving. In Japan, they are served in miso soup, whereas Chinese chefs tend to sauté them into vegetable dishes. 

Medicinally, shiitake have been used for hundreds of years. They have potent antibacterial and antiviral properties and contain a chemical called lentinan which appears to help heal chromosomal damage caused by cancer chemotherapy. In fact, shiitake mushrooms contain all eight essential amino acids and plenty of helpful phytonutrients which improve blood flow and prevent plaque build-up in the walls of blood vessels, protecting against lifestyle-related cardiovascular disease.

Psilocybin (magic mushrooms)

One of the known psychedelic fungi, evidence of psilocybin consumption was shown in stone age artwork and Central and South American sculptures from the pre-Columbian era. Still awaiting FDA approval, research has demonstrated the potential of psilocybin to treat psychiatric or behavioural disorders, including addiction management. 

Johns Hopkins University found a significantly improved abstinence from tobacco use in subjects treated with psilocybin over twelve months, and another pilot study showed improved quality of life in those suffering from life-limiting cancer diagnoses. 

In November 2021, researchers at Penn State University’s College of Medicine reported that psilocybin mushroom consumption may lower risk of depression. The research was published in Sciencedirect Journal. 

Psilocybin is said to have the greatest risks from consumption in uncontrolled environments but also holds the most promise for hard-to-treat psychiatric conditions. It’s important to remember that it remains a Schedule I drug according to the DEA. Schedule I drugs, substances, or chemicals are defined as drugs with no currently accepted medical use and a high potential for abuse.


Covering around 400 species of fungi, the cordyceps are found across Asia, abundantly so in tropical forests. Incredibly, the fungus can achieve parasitic status not just on trees, but also in small insects too, hijacking the host’s organ function and eventually entirely replacing it. 

Cordyceps has been used in traditional Chinese medicine extensively for kidney conditions and impotency, as well as in lung or skin cancers. 

Interestingly, cordyceps are thought to increase the body’s production of the molecule adenosine triphosphate (ATP), which is essential for delivering energy to the muscles.

Cordyceps  also contain those wonderful antioxidants, which may explain the anti-aging effects purported in those who take cordyceps regularly.

Turkey Tail

Identified by its namesake, the turkey tail mushroom looks just like the tail plumage of a wild turkey. Similar to other edible fungi, it contains polysaccharides, including beta-glucans, which have been shown to improve the body’s innate immune response, particularly in the setting of cancer treatments, but also in the prevention and treatment of the common cold and influenza. 

In addition, turkey tail is an excellent source of probiotics that aid digestion and the proliferation of gut-friendly bacteria such as acidophilus and bifidobacterium.


With a bitter taste and better resigned to consumption in tea, the meshima mushroom grows wild on mulberry trees. 

It has been shown that the meshima mushroom has anti-breast cancer activity, backed by Harvard Medical School, though more research is needed. A number of the compounds isolated from meshima mushrooms were found to stimulate humoral immune function, and dampen inflammatory responses. 

Most popular in Korea, meshima is dried to a powder and steeped in hot water as a health tea as it has high levels of antioxidants – as much as vitamin C! Those with eczema may benefit from the anti-inflammatory effects of a skincare preparation containing meshima, and there is potential as well for skin cancer and melanoma prevention.

Snow Mushroom

Looking more like an underwater coral than a mushroom, the snow mushroom takes its name from its translucent, snowflake-like appearance, albeit with a gelatinous texture. 

Snow mushroom is found in abundance in the tropics surrounding the Equator and is used in Chinese cuisine for its flavorless texture in sweetened dishes. More recently, it has been used to make dessert, soups, drinks, and ice cream and has even been added to skincare products after being dubbed ‘the new hyaluronic acid’ for its antioxidant and anti-aging effects.

From teas to tinctures, stews to sweets, the beautiful benefits of mushrooms cannot be overstated! These fungi have been used for thousands of years. Many of the edible fungi on the market taste great and have fantastic health benefits to boot. They can boost our immune system, soothe inflamed skin, and may help in the fight against cancer and mental illness. In my book, they just might be the most super of all the superfoods!

XO - Serena

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